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Optical Probing of Hippocampal Function in a Mouse Model of Demyelination/Remyelination

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Abstract

Nonlinear microscopy of calcium sensors was used to record hippocampal activity during induced demyelination and remyelination of axons for 100 days. Substantial changes to firing rates were identified during demyelination with partial recovery upon remyelination.

© 2020 The Author(s)

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