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Laser-induced spectral diagnosis of atherosclerosis

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Abstract

Recent advances in medical diagnostics show native laser-induced fluorescence spectroscopy to be a promising new technique with applications in such diverse fields as dentistry1 and cancer detection.2 We have shown that fluorescence spectroscopy can be used to differentiate between the normal and atherosclerotic artery. Optical fibers have been successfully used to deliver laser light and collect resulting fluorescence, suggesting that in vivo diagnosis of atherosclerosis may be possible via a laser-based catheter.

© 1986 Optical Society of America

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