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Conferences > CLEO_AT > 2013 > ATh1N > ATh1N.3

Optimization of Illumination Frequency and Preclinical Validation of a Wide-field Structured Illumination Microscope Designed for Imaging in situ Tumor Margins

Henry L. Fu, Jenna L. Mueller, Melodi Javid, David G. Kirsch, Nimmi Ramanujam, and J. Quincy Brown

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Abstract

We present a widefield structured illumination microscope for imaging surgical tumor margins in situ. The impact of frequency and turbidity on optical section thickness and SNR was characterized to determine the optimal imaging frequency.

© 2013 Optical Society of America

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