Abstract

Progress from an idea into a high resolution microscopy application since the invention of Fresnel Incoherent Correlation Holography (FINCH) [1] will be chronicled. In its current state of development, picture perfect 3D images with resolution about two times better than the Rayleigh limit can be reconstructed from FINCH holograms acquired by fluorescence microscopy. A number of optical, electro-optical and computational advances by ours and other laboratories have made this possible. Those advances, including the introduction of liquid crystal optics [2] in place of spatial light modulators and other new approaches will be discussed.

© 2014 Optical Society of America