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Electrophoretic Separation and Detection of a Few DNA Molecules in an Optofluidic Chip

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Abstract

After electrophoretic separation of dye-labeled DNA molecules of 17 different sizes, integrated-waveguide laser excitation and physical or numerical lock-in amplification enables a limit of detection down to 8-9 DNA molecules in an optofluidic chip.

© 2010 Optical Society of America

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