Coming to Grips with Amyloid Oligomers: Single Molecule Photobleaching Approaches

Vinod Subramaniam; Vinod Subramaniam

doi:10.1364/SENSORS.2014.SeM3C.1

Advanced Photonics
OSA Technical Digest (online) (Optica Publishing Group, 2014),
paper SeM3C.1
•https://doi.org/10.1364/SENSORS.2014.SeM3C.1

Coming to Grips with Amyloid Oligomers: Single Molecule Photobleaching Approaches

Vinod Subramaniam

Optical Sensors 2014

Barcelona Spain
27–31 July 2014
ISBN: 978-1-55752-820-9

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Nanophotonic and Plasmonic Biosensors II (SeM3C)

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V. Subramaniam, "Coming to Grips with Amyloid Oligomers: Single Molecule Photobleaching Approaches," in Advanced Photonics, OSA Technical Digest (online) (Optica Publishing Group, 2014), paper SeM3C.1.

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Abstract

We report on using single molecule photobleaching spectroscopy to determine the molecular aggregation number of specific nanometer-scale supramolecular oligomeric aggregates formed by the misfolding and self-assembly of proteins involved in neurodegenerative diseases.

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