Abstract

Automatic delineation and segmentation of airway structures from endoscopic optical coherence tomography (OCT) images improve image analysis efficiency and thus has been of particular interest. Conventional two-dimensional automatic segmentation methods, such as the dynamic programming approach, ensures the edge-continuity in the xz-direction (intra-B-scan), but fails to preserve the surface-continuity when concerning the y-direction (inter-B-scan). To solve this, we present a novel automatic three-dimensional (3D) airway segmentation strategy. Our segmentation scheme includes an artifact-oriented pre-processing pipeline and a modified 3D optimal graph search algorithm incorporating adaptive tissue-curvature adjustment. The proposed algorithm is tested on endoscopic airway OCT image data sets acquired by different swept-source OCT platforms, and on different animal and human models. With our method, the results show continuous surface segmentation performance, which is both robust and accurate.

© 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

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2018 (4)

2017 (3)

2016 (1)

J. C. Jing, L. Chou, E. Su, B. J. Wong, and Z. Chen, “Anatomically correct visualization of the human upper airway using a high-speed long range optical coherence tomography system with an integrated positioning sensor,” Sci. Rep. 6(1), 39443 (2016).
[Crossref] [PubMed]

2015 (2)

L. Qi, S. Huang, A. E. Heidari, C. Dai, J. Zhu, X. Zhang, and Z. Chen, “Automatic airway wall segmentation and thickness measurement for long-range optical coherence tomography images,” Opt. Express 23(26), 33992–34006 (2015).
[Crossref] [PubMed]

S. Huang, Z. Piao, J. Zhu, F. Lu, and Z. Chen, “In vivo microvascular network imaging of the human retina combined with an automatic three-dimensional segmentation method,” J. Biomed. Opt. 20(7), 076003 (2015).
[Crossref] [PubMed]

2014 (3)

M. Kirby, A. M. D. Lee, T. Candido, C. Macaulay, P. Lane, S. Lam, and H. O. Coxson, “Automated segmentation of porcine airway wall layers using optical coherence tomography: comparison with manual segmentation and histology,” Proc. SPIE 8927, 1–9 (2014).

K. Wijesundara, C. Zdanski, J. Kimbell, H. Price, N. Iftimia, and A. L. Oldenburg, “Quantitative upper airway endoscopy with swept-source anatomical optical coherence tomography,” Biomed. Opt. Express 5(3), 788–799 (2014).
[Crossref] [PubMed]

L. Chou, A. Batchinsky, S. Belenkiy, J. Jing, T. Ramalingam, M. Brenner, and Z. Chen, “In vivo detection of inhalation injury in large airway using three-dimensional long-range swept-source optical coherence tomography,” J. Biomed. Opt. 19(3), 036018 (2014).
[Crossref] [PubMed]

2013 (2)

2012 (1)

J. Jing, J. Zhang, A. C. Loy, B. J. F. Wong, and Z. Chen, “High-speed upper-airway imaging using full-range optical coherence tomography,” J. Biomed. Opt. 17(11), 110507 (2012).
[Crossref] [PubMed]

2011 (3)

S.-W. Lee, A. E. Heidary, D. Yoon, D. Mukai, T. Ramalingam, S. Mahon, J. Yin, J. Jing, G. Liu, Z. Chen, and M. Brenner, “Quantification of airway thickness changes in smoke-inhalation injury using in-vivo 3-D endoscopic frequency-domain optical coherence tomography,” Biomed. Opt. Express 2(2), 243–254 (2011).
[Crossref] [PubMed]

M. Heydarian, S. Choy, A. Wheatley, D. McCormack, H. O. Coxson, S. Lam, and G. Parraga, “Automated segmentation of lung airway wall area measurements from bronchoscopic Optical Coherence Tomography imaging,” Proc. SPIE 7965(519), 79651M (2011).
[Crossref]

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

2010 (1)

J. Yin, H. C. Yang, X. Li, J. Zhang, Q. Zhou, C. Hu, K. K. Shung, and Z. Chen, “Integrated intravascular optical coherence tomography ultrasound imaging system,” J. Biomed. Opt. 15(1), 010512 (2010).
[Crossref] [PubMed]

2009 (2)

J. Yin, G. Liu, J. Zhang, L. Yu, S. Mahon, D. Mukai, M. Brenner, and Z. Chen, “In vivo early detection of smoke-induced airway injury using three-dimensional swept-source optical coherence tomography,” J. Biomed. Opt. 14(6), 060503 (2009).
[Crossref] [PubMed]

M. K. Garvin, M. D. Abràmoff, X. Wu, S. R. Russell, T. L. Burns, and M. Sonka, “Automated 3-D intraretinal layer segmentation of macular spectral-domain optical coherence tomography images,” IEEE Trans. Med. Imaging 28(9), 1436–1447 (2009).
[Crossref] [PubMed]

2008 (5)

M. K. Garvin, M. D. Abràmoff, R. Kardon, S. R. Russell, X. Wu, and M. Sonka, “Intraretinal layer segmentation of macular optical coherence tomography images using optimal 3-D graph search,” IEEE Trans. Med. Imaging 27(10), 1495–1505 (2008).
[Crossref] [PubMed]

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

R. A. McLaughlin, J. P. Williamson, M. J. Phillips, J. J. Armstrong, S. Becker, D. R. Hillman, P. R. Eastwood, and D. D. Sampson, “Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway,” Opt. Express 16(22), 17521–17529 (2008).
[Crossref] [PubMed]

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

S. Lam, B. Standish, C. Baldwin, A. McWilliams, J. leRiche, A. Gazdar, A. I. Vitkin, V. Yang, N. Ikeda, and C. MacAulay, “In vivo optical coherence tomography imaging of preinvasive bronchial lesions,” Clin. Cancer Res. 14(7), 2006–2011 (2008).
[Crossref] [PubMed]

2007 (2)

B. J. Vakoc, M. Shishko, S. H. Yun, W. Y. Oh, M. J. Suter, A. E. Desjardins, J. A. Evans, N. S. Nishioka, G. J. Tearney, and B. E. Bouma, “Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video),” Gastrointest. Endosc. 65(6), 898–905 (2007).
[Crossref] [PubMed]

J. M. Ridgway, G. Ahuja, S. Guo, J. Su, U. Mahmood, Z. Chen, and B. Wong, “Imaging of the pediatric airway using optical coherence tomography,” Laryngoscope 117(12), 2206–2212 (2007).
[Crossref] [PubMed]

2006 (1)

K. Li, X. Wu, D. Z. Chen, and M. Sonka, “Optimal surface segmentation in volumetric images--a graph-theoretic approach,” IEEE Trans. Pattern Anal. Mach. Intell. 28(1), 119–134 (2006).
[Crossref] [PubMed]

2005 (2)

J. Zhang, J. S. Nelson, and Z. Chen, “Removal of a mirror image and enhancement of the signal-to-noise ratio in Fourier-domain optical coherence tomography using an electro-optic phase modulator,” Opt. Lett. 30(2), 147–149 (2005).
[Crossref] [PubMed]

B. J. Wong, R. P. Jackson, S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, “In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients,” Laryngoscope 115(11), 1904–1911 (2005).
[Crossref] [PubMed]

2004 (1)

Y. Boykov and V. Kolmogorov, “An experimental comparison of min-cut/max-flow algorithms for energy minimization in vision,” IEEE Trans. Pattern Anal. Mach. Intell. 26(9), 1124–1137 (2004).
[Crossref] [PubMed]

2003 (2)

B. E. Bouma, G. J. Tearney, H. Yabushita, M. Shishkov, C. R. Kauffman, D. DeJoseph Gauthier, B. D. MacNeill, S. L. Houser, H. T. Aretz, E. F. Halpern, and I. K. Jang, “Evaluation of intracoronary stenting by intravascular optical coherence tomography,” Heart 89(3), 317–320 (2003).
[Crossref] [PubMed]

R. A. Cox, A. S. Burke, K. Soejima, K. Murakami, J. Katahira, L. D. Traber, D. N. Herndon, F. C. Schmalstieg, D. L. Traber, and H. K. Hawkins, “Airway obstruction in sheep with burn and smoke inhalation injuries,” Am. J. Respir. Cell Mol. Biol. 29(3), 295–302 (2003).
[Crossref] [PubMed]

2002 (1)

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

1988 (1)

D. L. Traber, H. A. Linares, D. N. Herndon, and T. Prien, “The pathophysiology of inhalation injury--a review,” Burns 14(5), 357–364 (1988).
[Crossref] [PubMed]

Abràmoff, M. D.

M. K. Garvin, M. D. Abràmoff, X. Wu, S. R. Russell, T. L. Burns, and M. Sonka, “Automated 3-D intraretinal layer segmentation of macular spectral-domain optical coherence tomography images,” IEEE Trans. Med. Imaging 28(9), 1436–1447 (2009).
[Crossref] [PubMed]

M. K. Garvin, M. D. Abràmoff, R. Kardon, S. R. Russell, X. Wu, and M. Sonka, “Intraretinal layer segmentation of macular optical coherence tomography images using optimal 3-D graph search,” IEEE Trans. Med. Imaging 27(10), 1495–1505 (2008).
[Crossref] [PubMed]

Adams, D. C.

Ahuja, G.

J. M. Ridgway, G. Ahuja, S. Guo, J. Su, U. Mahmood, Z. Chen, and B. Wong, “Imaging of the pediatric airway using optical coherence tomography,” Laryngoscope 117(12), 2206–2212 (2007).
[Crossref] [PubMed]

Aretz, H. T.

B. E. Bouma, G. J. Tearney, H. Yabushita, M. Shishkov, C. R. Kauffman, D. DeJoseph Gauthier, B. D. MacNeill, S. L. Houser, H. T. Aretz, E. F. Halpern, and I. K. Jang, “Evaluation of intracoronary stenting by intravascular optical coherence tomography,” Heart 89(3), 317–320 (2003).
[Crossref] [PubMed]

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

Armstrong, J. J.

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

R. A. McLaughlin, J. P. Williamson, M. J. Phillips, J. J. Armstrong, S. Becker, D. R. Hillman, P. R. Eastwood, and D. D. Sampson, “Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway,” Opt. Express 16(22), 17521–17529 (2008).
[Crossref] [PubMed]

Armstrong, W. B.

B. J. Wong, R. P. Jackson, S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, “In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients,” Laryngoscope 115(11), 1904–1911 (2005).
[Crossref] [PubMed]

Bai, J.

Q. Song, J. Bai, M. K. Garvin, M. Sonka, J. M. Buatti, and X. Wu, “Optimal multiple surface segmentation with shape and context priors,” IEEE Trans. Med. Imaging 32(2), 376–386 (2013).
[Crossref] [PubMed]

Baker, V. A.

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

Baldwin, C.

S. Lam, B. Standish, C. Baldwin, A. McWilliams, J. leRiche, A. Gazdar, A. I. Vitkin, V. Yang, N. Ikeda, and C. MacAulay, “In vivo optical coherence tomography imaging of preinvasive bronchial lesions,” Clin. Cancer Res. 14(7), 2006–2011 (2008).
[Crossref] [PubMed]

Batchinsky, A.

L. Chou, A. Batchinsky, S. Belenkiy, J. Jing, T. Ramalingam, M. Brenner, and Z. Chen, “In vivo detection of inhalation injury in large airway using three-dimensional long-range swept-source optical coherence tomography,” J. Biomed. Opt. 19(3), 036018 (2014).
[Crossref] [PubMed]

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

Becker, S.

Belenkiy, S.

L. Chou, A. Batchinsky, S. Belenkiy, J. Jing, T. Ramalingam, M. Brenner, and Z. Chen, “In vivo detection of inhalation injury in large airway using three-dimensional long-range swept-source optical coherence tomography,” J. Biomed. Opt. 19(3), 036018 (2014).
[Crossref] [PubMed]

Boucher, R. C.

Bouma, B. E.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

B. J. Vakoc, M. Shishko, S. H. Yun, W. Y. Oh, M. J. Suter, A. E. Desjardins, J. A. Evans, N. S. Nishioka, G. J. Tearney, and B. E. Bouma, “Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video),” Gastrointest. Endosc. 65(6), 898–905 (2007).
[Crossref] [PubMed]

B. E. Bouma, G. J. Tearney, H. Yabushita, M. Shishkov, C. R. Kauffman, D. DeJoseph Gauthier, B. D. MacNeill, S. L. Houser, H. T. Aretz, E. F. Halpern, and I. K. Jang, “Evaluation of intracoronary stenting by intravascular optical coherence tomography,” Heart 89(3), 317–320 (2003).
[Crossref] [PubMed]

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

Boykov, Y.

Y. Boykov and V. Kolmogorov, “An experimental comparison of min-cut/max-flow algorithms for energy minimization in vision,” IEEE Trans. Pattern Anal. Mach. Intell. 26(9), 1124–1137 (2004).
[Crossref] [PubMed]

Brenner, M.

L. Chou, A. Batchinsky, S. Belenkiy, J. Jing, T. Ramalingam, M. Brenner, and Z. Chen, “In vivo detection of inhalation injury in large airway using three-dimensional long-range swept-source optical coherence tomography,” J. Biomed. Opt. 19(3), 036018 (2014).
[Crossref] [PubMed]

S.-W. Lee, A. E. Heidary, D. Yoon, D. Mukai, T. Ramalingam, S. Mahon, J. Yin, J. Jing, G. Liu, Z. Chen, and M. Brenner, “Quantification of airway thickness changes in smoke-inhalation injury using in-vivo 3-D endoscopic frequency-domain optical coherence tomography,” Biomed. Opt. Express 2(2), 243–254 (2011).
[Crossref] [PubMed]

J. Yin, G. Liu, J. Zhang, L. Yu, S. Mahon, D. Mukai, M. Brenner, and Z. Chen, “In vivo early detection of smoke-induced airway injury using three-dimensional swept-source optical coherence tomography,” J. Biomed. Opt. 14(6), 060503 (2009).
[Crossref] [PubMed]

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

Buatti, J. M.

Q. Song, J. Bai, M. K. Garvin, M. Sonka, J. M. Buatti, and X. Wu, “Optimal multiple surface segmentation with shape and context priors,” IEEE Trans. Med. Imaging 32(2), 376–386 (2013).
[Crossref] [PubMed]

Burke, A. S.

R. A. Cox, A. S. Burke, K. Soejima, K. Murakami, J. Katahira, L. D. Traber, D. N. Herndon, F. C. Schmalstieg, D. L. Traber, and H. K. Hawkins, “Airway obstruction in sheep with burn and smoke inhalation injuries,” Am. J. Respir. Cell Mol. Biol. 29(3), 295–302 (2003).
[Crossref] [PubMed]

Burney, T.

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

Burns, T. L.

M. K. Garvin, M. D. Abràmoff, X. Wu, S. R. Russell, T. L. Burns, and M. Sonka, “Automated 3-D intraretinal layer segmentation of macular spectral-domain optical coherence tomography images,” IEEE Trans. Med. Imaging 28(9), 1436–1447 (2009).
[Crossref] [PubMed]

Cable, A. E.

Cancio, L. C.

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

Candido, T.

M. Kirby, A. M. D. Lee, T. Candido, C. Macaulay, P. Lane, S. Lam, and H. O. Coxson, “Automated segmentation of porcine airway wall layers using optical coherence tomography: comparison with manual segmentation and histology,” Proc. SPIE 8927, 1–9 (2014).

Chen, D. Z.

K. Li, X. Wu, D. Z. Chen, and M. Sonka, “Optimal surface segmentation in volumetric images--a graph-theoretic approach,” IEEE Trans. Pattern Anal. Mach. Intell. 28(1), 119–134 (2006).
[Crossref] [PubMed]

Chen, Z.

Y. Li, J. Jing, J. Yu, B. Zhang, T. Huo, Q. Yang, and Z. Chen, “Multimodality endoscopic optical coherence tomography and fluorescence imaging technology for visualization of layered architecture and subsurface microvasculature,” Opt. Lett. 43(9), 2074–2077 (2018).
[Crossref] [PubMed]

Y. Li, J. Jing, E. Heidari, J. Zhu, Y. Qu, and Z. Chen, “Intravascular optical coherence tomography for characterization of atherosclerosis with a 1.7 micron swept-source laser,” Sci. Rep. 7(1), 14525 (2017).
[Crossref] [PubMed]

J. C. Jing, L. Chou, E. Su, B. J. Wong, and Z. Chen, “Anatomically correct visualization of the human upper airway using a high-speed long range optical coherence tomography system with an integrated positioning sensor,” Sci. Rep. 6(1), 39443 (2016).
[Crossref] [PubMed]

S. Huang, Z. Piao, J. Zhu, F. Lu, and Z. Chen, “In vivo microvascular network imaging of the human retina combined with an automatic three-dimensional segmentation method,” J. Biomed. Opt. 20(7), 076003 (2015).
[Crossref] [PubMed]

L. Qi, S. Huang, A. E. Heidari, C. Dai, J. Zhu, X. Zhang, and Z. Chen, “Automatic airway wall segmentation and thickness measurement for long-range optical coherence tomography images,” Opt. Express 23(26), 33992–34006 (2015).
[Crossref] [PubMed]

L. Chou, A. Batchinsky, S. Belenkiy, J. Jing, T. Ramalingam, M. Brenner, and Z. Chen, “In vivo detection of inhalation injury in large airway using three-dimensional long-range swept-source optical coherence tomography,” J. Biomed. Opt. 19(3), 036018 (2014).
[Crossref] [PubMed]

J. Jing, J. Zhang, A. C. Loy, B. J. F. Wong, and Z. Chen, “High-speed upper-airway imaging using full-range optical coherence tomography,” J. Biomed. Opt. 17(11), 110507 (2012).
[Crossref] [PubMed]

S.-W. Lee, A. E. Heidary, D. Yoon, D. Mukai, T. Ramalingam, S. Mahon, J. Yin, J. Jing, G. Liu, Z. Chen, and M. Brenner, “Quantification of airway thickness changes in smoke-inhalation injury using in-vivo 3-D endoscopic frequency-domain optical coherence tomography,” Biomed. Opt. Express 2(2), 243–254 (2011).
[Crossref] [PubMed]

J. Yin, H. C. Yang, X. Li, J. Zhang, Q. Zhou, C. Hu, K. K. Shung, and Z. Chen, “Integrated intravascular optical coherence tomography ultrasound imaging system,” J. Biomed. Opt. 15(1), 010512 (2010).
[Crossref] [PubMed]

J. Yin, G. Liu, J. Zhang, L. Yu, S. Mahon, D. Mukai, M. Brenner, and Z. Chen, “In vivo early detection of smoke-induced airway injury using three-dimensional swept-source optical coherence tomography,” J. Biomed. Opt. 14(6), 060503 (2009).
[Crossref] [PubMed]

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

J. M. Ridgway, G. Ahuja, S. Guo, J. Su, U. Mahmood, Z. Chen, and B. Wong, “Imaging of the pediatric airway using optical coherence tomography,” Laryngoscope 117(12), 2206–2212 (2007).
[Crossref] [PubMed]

B. J. Wong, R. P. Jackson, S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, “In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients,” Laryngoscope 115(11), 1904–1911 (2005).
[Crossref] [PubMed]

J. Zhang, J. S. Nelson, and Z. Chen, “Removal of a mirror image and enhancement of the signal-to-noise ratio in Fourier-domain optical coherence tomography using an electro-optic phase modulator,” Opt. Lett. 30(2), 147–149 (2005).
[Crossref] [PubMed]

Cho, J. L.

Choi, K. B.

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

Chou, L.

J. C. Jing, L. Chou, E. Su, B. J. Wong, and Z. Chen, “Anatomically correct visualization of the human upper airway using a high-speed long range optical coherence tomography system with an integrated positioning sensor,” Sci. Rep. 6(1), 39443 (2016).
[Crossref] [PubMed]

L. Chou, A. Batchinsky, S. Belenkiy, J. Jing, T. Ramalingam, M. Brenner, and Z. Chen, “In vivo detection of inhalation injury in large airway using three-dimensional long-range swept-source optical coherence tomography,” J. Biomed. Opt. 19(3), 036018 (2014).
[Crossref] [PubMed]

Choy, S.

M. Heydarian, S. Choy, A. Wheatley, D. McCormack, H. O. Coxson, S. Lam, and G. Parraga, “Automated segmentation of lung airway wall area measurements from bronchoscopic Optical Coherence Tomography imaging,” Proc. SPIE 7965(519), 79651M (2011).
[Crossref]

Cole, E.

T. B. Dubose, D. Cunefare, E. Cole, P. Milanfar, J. A. Izatt, and S. Farsiu, “Statistical models of signal and noise and fundamental limits of segmentation accuracy in retinal optical coherence tomography,” IEEE Trans. Med. Imaging 37(9), 1978–1988 (2018).
[Crossref] [PubMed]

Cox, R. A.

R. A. Cox, A. S. Burke, K. Soejima, K. Murakami, J. Katahira, L. D. Traber, D. N. Herndon, F. C. Schmalstieg, D. L. Traber, and H. K. Hawkins, “Airway obstruction in sheep with burn and smoke inhalation injuries,” Am. J. Respir. Cell Mol. Biol. 29(3), 295–302 (2003).
[Crossref] [PubMed]

Coxson, H. O.

M. Kirby, A. M. D. Lee, T. Candido, C. Macaulay, P. Lane, S. Lam, and H. O. Coxson, “Automated segmentation of porcine airway wall layers using optical coherence tomography: comparison with manual segmentation and histology,” Proc. SPIE 8927, 1–9 (2014).

M. Heydarian, S. Choy, A. Wheatley, D. McCormack, H. O. Coxson, S. Lam, and G. Parraga, “Automated segmentation of lung airway wall area measurements from bronchoscopic Optical Coherence Tomography imaging,” Proc. SPIE 7965(519), 79651M (2011).
[Crossref]

Crumley, R. L.

B. J. Wong, R. P. Jackson, S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, “In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients,” Laryngoscope 115(11), 1904–1911 (2005).
[Crossref] [PubMed]

Cunefare, D.

T. B. Dubose, D. Cunefare, E. Cole, P. Milanfar, J. A. Izatt, and S. Farsiu, “Statistical models of signal and noise and fundamental limits of segmentation accuracy in retinal optical coherence tomography,” IEEE Trans. Med. Imaging 37(9), 1978–1988 (2018).
[Crossref] [PubMed]

Curatolo, A.

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

Dai, C.

DeJoseph Gauthier, D.

B. E. Bouma, G. J. Tearney, H. Yabushita, M. Shishkov, C. R. Kauffman, D. DeJoseph Gauthier, B. D. MacNeill, S. L. Houser, H. T. Aretz, E. F. Halpern, and I. K. Jang, “Evaluation of intracoronary stenting by intravascular optical coherence tomography,” Heart 89(3), 317–320 (2003).
[Crossref] [PubMed]

Desjardins, A. E.

B. J. Vakoc, M. Shishko, S. H. Yun, W. Y. Oh, M. J. Suter, A. E. Desjardins, J. A. Evans, N. S. Nishioka, G. J. Tearney, and B. E. Bouma, “Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video),” Gastrointest. Endosc. 65(6), 898–905 (2007).
[Crossref] [PubMed]

Dubose, T. B.

T. B. Dubose, D. Cunefare, E. Cole, P. Milanfar, J. A. Izatt, and S. Farsiu, “Statistical models of signal and noise and fundamental limits of segmentation accuracy in retinal optical coherence tomography,” IEEE Trans. Med. Imaging 37(9), 1978–1988 (2018).
[Crossref] [PubMed]

Eastwood, P. R.

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

R. A. McLaughlin, J. P. Williamson, M. J. Phillips, J. J. Armstrong, S. Becker, D. R. Hillman, P. R. Eastwood, and D. D. Sampson, “Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway,” Opt. Express 16(22), 17521–17529 (2008).
[Crossref] [PubMed]

Evans, J. A.

B. J. Vakoc, M. Shishko, S. H. Yun, W. Y. Oh, M. J. Suter, A. E. Desjardins, J. A. Evans, N. S. Nishioka, G. J. Tearney, and B. E. Bouma, “Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video),” Gastrointest. Endosc. 65(6), 898–905 (2007).
[Crossref] [PubMed]

Farsiu, S.

T. B. Dubose, D. Cunefare, E. Cole, P. Milanfar, J. A. Izatt, and S. Farsiu, “Statistical models of signal and noise and fundamental limits of segmentation accuracy in retinal optical coherence tomography,” IEEE Trans. Med. Imaging 37(9), 1978–1988 (2018).
[Crossref] [PubMed]

Fujimoto, J. G.

Gan, M.

Garvin, M. K.

Q. Song, J. Bai, M. K. Garvin, M. Sonka, J. M. Buatti, and X. Wu, “Optimal multiple surface segmentation with shape and context priors,” IEEE Trans. Med. Imaging 32(2), 376–386 (2013).
[Crossref] [PubMed]

M. K. Garvin, M. D. Abràmoff, X. Wu, S. R. Russell, T. L. Burns, and M. Sonka, “Automated 3-D intraretinal layer segmentation of macular spectral-domain optical coherence tomography images,” IEEE Trans. Med. Imaging 28(9), 1436–1447 (2009).
[Crossref] [PubMed]

M. K. Garvin, M. D. Abràmoff, R. Kardon, S. R. Russell, X. Wu, and M. Sonka, “Intraretinal layer segmentation of macular optical coherence tomography images using optimal 3-D graph search,” IEEE Trans. Med. Imaging 27(10), 1495–1505 (2008).
[Crossref] [PubMed]

Gazdar, A.

S. Lam, B. Standish, C. Baldwin, A. McWilliams, J. leRiche, A. Gazdar, A. I. Vitkin, V. Yang, N. Ikeda, and C. MacAulay, “In vivo optical coherence tomography imaging of preinvasive bronchial lesions,” Clin. Cancer Res. 14(7), 2006–2011 (2008).
[Crossref] [PubMed]

Gu, M.

B. J. Wong, R. P. Jackson, S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, “In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients,” Laryngoscope 115(11), 1904–1911 (2005).
[Crossref] [PubMed]

Guo, S.

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

J. M. Ridgway, G. Ahuja, S. Guo, J. Su, U. Mahmood, Z. Chen, and B. Wong, “Imaging of the pediatric airway using optical coherence tomography,” Laryngoscope 117(12), 2206–2212 (2007).
[Crossref] [PubMed]

B. J. Wong, R. P. Jackson, S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, “In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients,” Laryngoscope 115(11), 1904–1911 (2005).
[Crossref] [PubMed]

Halpern, E. F.

B. E. Bouma, G. J. Tearney, H. Yabushita, M. Shishkov, C. R. Kauffman, D. DeJoseph Gauthier, B. D. MacNeill, S. L. Houser, H. T. Aretz, E. F. Halpern, and I. K. Jang, “Evaluation of intracoronary stenting by intravascular optical coherence tomography,” Heart 89(3), 317–320 (2003).
[Crossref] [PubMed]

Hamilos, D. L.

Hawkins, H. K.

R. A. Cox, A. S. Burke, K. Soejima, K. Murakami, J. Katahira, L. D. Traber, D. N. Herndon, F. C. Schmalstieg, D. L. Traber, and H. K. Hawkins, “Airway obstruction in sheep with burn and smoke inhalation injuries,” Am. J. Respir. Cell Mol. Biol. 29(3), 295–302 (2003).
[Crossref] [PubMed]

Heidari, A. E.

Heidari, E.

Y. Li, J. Jing, E. Heidari, J. Zhu, Y. Qu, and Z. Chen, “Intravascular optical coherence tomography for characterization of atherosclerosis with a 1.7 micron swept-source laser,” Sci. Rep. 7(1), 14525 (2017).
[Crossref] [PubMed]

Heidary, A. E.

Heim, P. J.

Herndon, D. N.

R. A. Cox, A. S. Burke, K. Soejima, K. Murakami, J. Katahira, L. D. Traber, D. N. Herndon, F. C. Schmalstieg, D. L. Traber, and H. K. Hawkins, “Airway obstruction in sheep with burn and smoke inhalation injuries,” Am. J. Respir. Cell Mol. Biol. 29(3), 295–302 (2003).
[Crossref] [PubMed]

D. L. Traber, H. A. Linares, D. N. Herndon, and T. Prien, “The pathophysiology of inhalation injury--a review,” Burns 14(5), 357–364 (1988).
[Crossref] [PubMed]

Heydarian, M.

M. Heydarian, S. Choy, A. Wheatley, D. McCormack, H. O. Coxson, S. Lam, and G. Parraga, “Automated segmentation of lung airway wall area measurements from bronchoscopic Optical Coherence Tomography imaging,” Proc. SPIE 7965(519), 79651M (2011).
[Crossref]

Hillman, D. R.

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

R. A. McLaughlin, J. P. Williamson, M. J. Phillips, J. J. Armstrong, S. Becker, D. R. Hillman, P. R. Eastwood, and D. D. Sampson, “Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway,” Opt. Express 16(22), 17521–17529 (2008).
[Crossref] [PubMed]

Hornegger, J.

Houser, S. L.

B. E. Bouma, G. J. Tearney, H. Yabushita, M. Shishkov, C. R. Kauffman, D. DeJoseph Gauthier, B. D. MacNeill, S. L. Houser, H. T. Aretz, E. F. Halpern, and I. K. Jang, “Evaluation of intracoronary stenting by intravascular optical coherence tomography,” Heart 89(3), 317–320 (2003).
[Crossref] [PubMed]

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

Hu, C.

J. Yin, H. C. Yang, X. Li, J. Zhang, Q. Zhou, C. Hu, K. K. Shung, and Z. Chen, “Integrated intravascular optical coherence tomography ultrasound imaging system,” J. Biomed. Opt. 15(1), 010512 (2010).
[Crossref] [PubMed]

Huang, S.

L. Qi, S. Huang, A. E. Heidari, C. Dai, J. Zhu, X. Zhang, and Z. Chen, “Automatic airway wall segmentation and thickness measurement for long-range optical coherence tomography images,” Opt. Express 23(26), 33992–34006 (2015).
[Crossref] [PubMed]

S. Huang, Z. Piao, J. Zhu, F. Lu, and Z. Chen, “In vivo microvascular network imaging of the human retina combined with an automatic three-dimensional segmentation method,” J. Biomed. Opt. 20(7), 076003 (2015).
[Crossref] [PubMed]

Huo, T.

Iftimia, N.

Ikeda, N.

S. Lam, B. Standish, C. Baldwin, A. McWilliams, J. leRiche, A. Gazdar, A. I. Vitkin, V. Yang, N. Ikeda, and C. MacAulay, “In vivo optical coherence tomography imaging of preinvasive bronchial lesions,” Clin. Cancer Res. 14(7), 2006–2011 (2008).
[Crossref] [PubMed]

Izatt, J. A.

T. B. Dubose, D. Cunefare, E. Cole, P. Milanfar, J. A. Izatt, and S. Farsiu, “Statistical models of signal and noise and fundamental limits of segmentation accuracy in retinal optical coherence tomography,” IEEE Trans. Med. Imaging 37(9), 1978–1988 (2018).
[Crossref] [PubMed]

Jackson, R. P.

B. J. Wong, R. P. Jackson, S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, “In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients,” Laryngoscope 115(11), 1904–1911 (2005).
[Crossref] [PubMed]

James, A. L.

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

Jang, I. K.

B. E. Bouma, G. J. Tearney, H. Yabushita, M. Shishkov, C. R. Kauffman, D. DeJoseph Gauthier, B. D. MacNeill, S. L. Houser, H. T. Aretz, E. F. Halpern, and I. K. Jang, “Evaluation of intracoronary stenting by intravascular optical coherence tomography,” Heart 89(3), 317–320 (2003).
[Crossref] [PubMed]

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

Jayaraman, V.

Jiang, J.

Jing, J.

Y. Li, J. Jing, J. Yu, B. Zhang, T. Huo, Q. Yang, and Z. Chen, “Multimodality endoscopic optical coherence tomography and fluorescence imaging technology for visualization of layered architecture and subsurface microvasculature,” Opt. Lett. 43(9), 2074–2077 (2018).
[Crossref] [PubMed]

Y. Li, J. Jing, E. Heidari, J. Zhu, Y. Qu, and Z. Chen, “Intravascular optical coherence tomography for characterization of atherosclerosis with a 1.7 micron swept-source laser,” Sci. Rep. 7(1), 14525 (2017).
[Crossref] [PubMed]

L. Chou, A. Batchinsky, S. Belenkiy, J. Jing, T. Ramalingam, M. Brenner, and Z. Chen, “In vivo detection of inhalation injury in large airway using three-dimensional long-range swept-source optical coherence tomography,” J. Biomed. Opt. 19(3), 036018 (2014).
[Crossref] [PubMed]

J. Jing, J. Zhang, A. C. Loy, B. J. F. Wong, and Z. Chen, “High-speed upper-airway imaging using full-range optical coherence tomography,” J. Biomed. Opt. 17(11), 110507 (2012).
[Crossref] [PubMed]

S.-W. Lee, A. E. Heidary, D. Yoon, D. Mukai, T. Ramalingam, S. Mahon, J. Yin, J. Jing, G. Liu, Z. Chen, and M. Brenner, “Quantification of airway thickness changes in smoke-inhalation injury using in-vivo 3-D endoscopic frequency-domain optical coherence tomography,” Biomed. Opt. Express 2(2), 243–254 (2011).
[Crossref] [PubMed]

Jing, J. C.

J. C. Jing, L. Chou, E. Su, B. J. Wong, and Z. Chen, “Anatomically correct visualization of the human upper airway using a high-speed long range optical coherence tomography system with an integrated positioning sensor,” Sci. Rep. 6(1), 39443 (2016).
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Ju, J.

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

Kang, D. H.

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

Kardon, R.

M. K. Garvin, M. D. Abràmoff, R. Kardon, S. R. Russell, X. Wu, and M. Sonka, “Intraretinal layer segmentation of macular optical coherence tomography images using optimal 3-D graph search,” IEEE Trans. Med. Imaging 27(10), 1495–1505 (2008).
[Crossref] [PubMed]

Katahira, J.

R. A. Cox, A. S. Burke, K. Soejima, K. Murakami, J. Katahira, L. D. Traber, D. N. Herndon, F. C. Schmalstieg, D. L. Traber, and H. K. Hawkins, “Airway obstruction in sheep with burn and smoke inhalation injuries,” Am. J. Respir. Cell Mol. Biol. 29(3), 295–302 (2003).
[Crossref] [PubMed]

Kauffman, C. R.

B. E. Bouma, G. J. Tearney, H. Yabushita, M. Shishkov, C. R. Kauffman, D. DeJoseph Gauthier, B. D. MacNeill, S. L. Houser, H. T. Aretz, E. F. Halpern, and I. K. Jang, “Evaluation of intracoronary stenting by intravascular optical coherence tomography,” Heart 89(3), 317–320 (2003).
[Crossref] [PubMed]

Kesimer, M.

Kimbell, J.

Kirby, M.

M. Kirby, A. M. D. Lee, T. Candido, C. Macaulay, P. Lane, S. Lam, and H. O. Coxson, “Automated segmentation of porcine airway wall layers using optical coherence tomography: comparison with manual segmentation and histology,” Proc. SPIE 8927, 1–9 (2014).

Kolmogorov, V.

Y. Boykov and V. Kolmogorov, “An experimental comparison of min-cut/max-flow algorithms for energy minimization in vision,” IEEE Trans. Pattern Anal. Mach. Intell. 26(9), 1124–1137 (2004).
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Kraus, M. F.

Kreuter, K.

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
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Lam, S.

M. Kirby, A. M. D. Lee, T. Candido, C. Macaulay, P. Lane, S. Lam, and H. O. Coxson, “Automated segmentation of porcine airway wall layers using optical coherence tomography: comparison with manual segmentation and histology,” Proc. SPIE 8927, 1–9 (2014).

M. Heydarian, S. Choy, A. Wheatley, D. McCormack, H. O. Coxson, S. Lam, and G. Parraga, “Automated segmentation of lung airway wall area measurements from bronchoscopic Optical Coherence Tomography imaging,” Proc. SPIE 7965(519), 79651M (2011).
[Crossref]

S. Lam, B. Standish, C. Baldwin, A. McWilliams, J. leRiche, A. Gazdar, A. I. Vitkin, V. Yang, N. Ikeda, and C. MacAulay, “In vivo optical coherence tomography imaging of preinvasive bronchial lesions,” Clin. Cancer Res. 14(7), 2006–2011 (2008).
[Crossref] [PubMed]

Lane, P.

M. Kirby, A. M. D. Lee, T. Candido, C. Macaulay, P. Lane, S. Lam, and H. O. Coxson, “Automated segmentation of porcine airway wall layers using optical coherence tomography: comparison with manual segmentation and histology,” Proc. SPIE 8927, 1–9 (2014).

Lauwers, G. Y.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

Lee, A. M. D.

M. Kirby, A. M. D. Lee, T. Candido, C. Macaulay, P. Lane, S. Lam, and H. O. Coxson, “Automated segmentation of porcine airway wall layers using optical coherence tomography: comparison with manual segmentation and histology,” Proc. SPIE 8927, 1–9 (2014).

Lee, S.-W.

leRiche, J.

S. Lam, B. Standish, C. Baldwin, A. McWilliams, J. leRiche, A. Gazdar, A. I. Vitkin, V. Yang, N. Ikeda, and C. MacAulay, “In vivo optical coherence tomography imaging of preinvasive bronchial lesions,” Clin. Cancer Res. 14(7), 2006–2011 (2008).
[Crossref] [PubMed]

Li, K.

K. Li, X. Wu, D. Z. Chen, and M. Sonka, “Optimal surface segmentation in volumetric images--a graph-theoretic approach,” IEEE Trans. Pattern Anal. Mach. Intell. 28(1), 119–134 (2006).
[Crossref] [PubMed]

Li, X.

Li, Y.

Y. Li, J. Jing, J. Yu, B. Zhang, T. Huo, Q. Yang, and Z. Chen, “Multimodality endoscopic optical coherence tomography and fluorescence imaging technology for visualization of layered architecture and subsurface microvasculature,” Opt. Lett. 43(9), 2074–2077 (2018).
[Crossref] [PubMed]

Y. Li, J. Jing, E. Heidari, J. Zhu, Y. Qu, and Z. Chen, “Intravascular optical coherence tomography for characterization of atherosclerosis with a 1.7 micron swept-source laser,” Sci. Rep. 7(1), 14525 (2017).
[Crossref] [PubMed]

Liang, W.

Liang, Y.

Linares, H. A.

D. L. Traber, H. A. Linares, D. N. Herndon, and T. Prien, “The pathophysiology of inhalation injury--a review,” Burns 14(5), 357–364 (1988).
[Crossref] [PubMed]

Liu, G.

S.-W. Lee, A. E. Heidary, D. Yoon, D. Mukai, T. Ramalingam, S. Mahon, J. Yin, J. Jing, G. Liu, Z. Chen, and M. Brenner, “Quantification of airway thickness changes in smoke-inhalation injury using in-vivo 3-D endoscopic frequency-domain optical coherence tomography,” Biomed. Opt. Express 2(2), 243–254 (2011).
[Crossref] [PubMed]

J. Yin, G. Liu, J. Zhang, L. Yu, S. Mahon, D. Mukai, M. Brenner, and Z. Chen, “In vivo early detection of smoke-induced airway injury using three-dimensional swept-source optical coherence tomography,” J. Biomed. Opt. 14(6), 060503 (2009).
[Crossref] [PubMed]

Loy, A. C.

J. Jing, J. Zhang, A. C. Loy, B. J. F. Wong, and Z. Chen, “High-speed upper-airway imaging using full-range optical coherence tomography,” J. Biomed. Opt. 17(11), 110507 (2012).
[Crossref] [PubMed]

Lu, F.

S. Huang, Z. Piao, J. Zhu, F. Lu, and Z. Chen, “In vivo microvascular network imaging of the human retina combined with an automatic three-dimensional segmentation method,” J. Biomed. Opt. 20(7), 076003 (2015).
[Crossref] [PubMed]

Luster, A. D.

Macaulay, C.

M. Kirby, A. M. D. Lee, T. Candido, C. Macaulay, P. Lane, S. Lam, and H. O. Coxson, “Automated segmentation of porcine airway wall layers using optical coherence tomography: comparison with manual segmentation and histology,” Proc. SPIE 8927, 1–9 (2014).

S. Lam, B. Standish, C. Baldwin, A. McWilliams, J. leRiche, A. Gazdar, A. I. Vitkin, V. Yang, N. Ikeda, and C. MacAulay, “In vivo optical coherence tomography imaging of preinvasive bronchial lesions,” Clin. Cancer Res. 14(7), 2006–2011 (2008).
[Crossref] [PubMed]

MacNeill, B. D.

B. E. Bouma, G. J. Tearney, H. Yabushita, M. Shishkov, C. R. Kauffman, D. DeJoseph Gauthier, B. D. MacNeill, S. L. Houser, H. T. Aretz, E. F. Halpern, and I. K. Jang, “Evaluation of intracoronary stenting by intravascular optical coherence tomography,” Heart 89(3), 317–320 (2003).
[Crossref] [PubMed]

Mahmood, U.

J. M. Ridgway, G. Ahuja, S. Guo, J. Su, U. Mahmood, Z. Chen, and B. Wong, “Imaging of the pediatric airway using optical coherence tomography,” Laryngoscope 117(12), 2206–2212 (2007).
[Crossref] [PubMed]

B. J. Wong, R. P. Jackson, S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, “In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients,” Laryngoscope 115(11), 1904–1911 (2005).
[Crossref] [PubMed]

Mahon, S.

S.-W. Lee, A. E. Heidary, D. Yoon, D. Mukai, T. Ramalingam, S. Mahon, J. Yin, J. Jing, G. Liu, Z. Chen, and M. Brenner, “Quantification of airway thickness changes in smoke-inhalation injury using in-vivo 3-D endoscopic frequency-domain optical coherence tomography,” Biomed. Opt. Express 2(2), 243–254 (2011).
[Crossref] [PubMed]

J. Yin, G. Liu, J. Zhang, L. Yu, S. Mahon, D. Mukai, M. Brenner, and Z. Chen, “In vivo early detection of smoke-induced airway injury using three-dimensional swept-source optical coherence tomography,” J. Biomed. Opt. 14(6), 060503 (2009).
[Crossref] [PubMed]

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

Marks, G. B.

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

Mashimo, H.

McCormack, D.

M. Heydarian, S. Choy, A. Wheatley, D. McCormack, H. O. Coxson, S. Lam, and G. Parraga, “Automated segmentation of lung airway wall area measurements from bronchoscopic Optical Coherence Tomography imaging,” Proc. SPIE 7965(519), 79651M (2011).
[Crossref]

McLaughlin, R. A.

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

R. A. McLaughlin, J. P. Williamson, M. J. Phillips, J. J. Armstrong, S. Becker, D. R. Hillman, P. R. Eastwood, and D. D. Sampson, “Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway,” Opt. Express 16(22), 17521–17529 (2008).
[Crossref] [PubMed]

McWilliams, A.

S. Lam, B. Standish, C. Baldwin, A. McWilliams, J. leRiche, A. Gazdar, A. I. Vitkin, V. Yang, N. Ikeda, and C. MacAulay, “In vivo optical coherence tomography imaging of preinvasive bronchial lesions,” Clin. Cancer Res. 14(7), 2006–2011 (2008).
[Crossref] [PubMed]

Medoff, B. D.

Milanfar, P.

T. B. Dubose, D. Cunefare, E. Cole, P. Milanfar, J. A. Izatt, and S. Farsiu, “Statistical models of signal and noise and fundamental limits of segmentation accuracy in retinal optical coherence tomography,” IEEE Trans. Med. Imaging 37(9), 1978–1988 (2018).
[Crossref] [PubMed]

Mino-Kenudson, M.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

Mukai, D.

S.-W. Lee, A. E. Heidary, D. Yoon, D. Mukai, T. Ramalingam, S. Mahon, J. Yin, J. Jing, G. Liu, Z. Chen, and M. Brenner, “Quantification of airway thickness changes in smoke-inhalation injury using in-vivo 3-D endoscopic frequency-domain optical coherence tomography,” Biomed. Opt. Express 2(2), 243–254 (2011).
[Crossref] [PubMed]

J. Yin, G. Liu, J. Zhang, L. Yu, S. Mahon, D. Mukai, M. Brenner, and Z. Chen, “In vivo early detection of smoke-induced airway injury using three-dimensional swept-source optical coherence tomography,” J. Biomed. Opt. 14(6), 060503 (2009).
[Crossref] [PubMed]

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

Murakami, K.

R. A. Cox, A. S. Burke, K. Soejima, K. Murakami, J. Katahira, L. D. Traber, D. N. Herndon, F. C. Schmalstieg, D. L. Traber, and H. K. Hawkins, “Airway obstruction in sheep with burn and smoke inhalation injuries,” Am. J. Respir. Cell Mol. Biol. 29(3), 295–302 (2003).
[Crossref] [PubMed]

Narula, N.

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

Nelson, J. S.

Nishioka, N. S.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

B. J. Vakoc, M. Shishko, S. H. Yun, W. Y. Oh, M. J. Suter, A. E. Desjardins, J. A. Evans, N. S. Nishioka, G. J. Tearney, and B. E. Bouma, “Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video),” Gastrointest. Endosc. 65(6), 898–905 (2007).
[Crossref] [PubMed]

Noffsinger, W. J.

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

Oh, W. Y.

B. J. Vakoc, M. Shishko, S. H. Yun, W. Y. Oh, M. J. Suter, A. E. Desjardins, J. A. Evans, N. S. Nishioka, G. J. Tearney, and B. E. Bouma, “Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video),” Gastrointest. Endosc. 65(6), 898–905 (2007).
[Crossref] [PubMed]

Oldenburg, A. L.

Pahlevaninezhad, H.

Park, S. J.

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

Park, S. W.

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

Parraga, G.

M. Heydarian, S. Choy, A. Wheatley, D. McCormack, H. O. Coxson, S. Lam, and G. Parraga, “Automated segmentation of lung airway wall area measurements from bronchoscopic Optical Coherence Tomography imaging,” Proc. SPIE 7965(519), 79651M (2011).
[Crossref]

Phillips, M. J.

Piao, Z.

S. Huang, Z. Piao, J. Zhu, F. Lu, and Z. Chen, “In vivo microvascular network imaging of the human retina combined with an automatic three-dimensional segmentation method,” J. Biomed. Opt. 20(7), 076003 (2015).
[Crossref] [PubMed]

Pomerantsev, E.

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

Potsaid, B.

Price, H.

Prien, T.

D. L. Traber, H. A. Linares, D. N. Herndon, and T. Prien, “The pathophysiology of inhalation injury--a review,” Burns 14(5), 357–364 (1988).
[Crossref] [PubMed]

Qi, L.

Qu, Y.

Y. Li, J. Jing, E. Heidari, J. Zhu, Y. Qu, and Z. Chen, “Intravascular optical coherence tomography for characterization of atherosclerosis with a 1.7 micron swept-source laser,” Sci. Rep. 7(1), 14525 (2017).
[Crossref] [PubMed]

Ramalingam, T.

L. Chou, A. Batchinsky, S. Belenkiy, J. Jing, T. Ramalingam, M. Brenner, and Z. Chen, “In vivo detection of inhalation injury in large airway using three-dimensional long-range swept-source optical coherence tomography,” J. Biomed. Opt. 19(3), 036018 (2014).
[Crossref] [PubMed]

S.-W. Lee, A. E. Heidary, D. Yoon, D. Mukai, T. Ramalingam, S. Mahon, J. Yin, J. Jing, G. Liu, Z. Chen, and M. Brenner, “Quantification of airway thickness changes in smoke-inhalation injury using in-vivo 3-D endoscopic frequency-domain optical coherence tomography,” Biomed. Opt. Express 2(2), 243–254 (2011).
[Crossref] [PubMed]

Regli, A.

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

Ridgway, J. M.

J. M. Ridgway, G. Ahuja, S. Guo, J. Su, U. Mahmood, Z. Chen, and B. Wong, “Imaging of the pediatric airway using optical coherence tomography,” Laryngoscope 117(12), 2206–2212 (2007).
[Crossref] [PubMed]

B. J. Wong, R. P. Jackson, S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, “In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients,” Laryngoscope 115(11), 1904–1911 (2005).
[Crossref] [PubMed]

Russell, S. R.

M. K. Garvin, M. D. Abràmoff, X. Wu, S. R. Russell, T. L. Burns, and M. Sonka, “Automated 3-D intraretinal layer segmentation of macular spectral-domain optical coherence tomography images,” IEEE Trans. Med. Imaging 28(9), 1436–1447 (2009).
[Crossref] [PubMed]

M. K. Garvin, M. D. Abràmoff, R. Kardon, S. R. Russell, X. Wu, and M. Sonka, “Intraretinal layer segmentation of macular optical coherence tomography images using optimal 3-D graph search,” IEEE Trans. Med. Imaging 27(10), 1495–1505 (2008).
[Crossref] [PubMed]

Sampson, D. D.

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

R. A. McLaughlin, J. P. Williamson, M. J. Phillips, J. J. Armstrong, S. Becker, D. R. Hillman, P. R. Eastwood, and D. D. Sampson, “Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway,” Opt. Express 16(22), 17521–17529 (2008).
[Crossref] [PubMed]

Schlendorf, K.

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

Schmalstieg, F. C.

R. A. Cox, A. S. Burke, K. Soejima, K. Murakami, J. Katahira, L. D. Traber, D. N. Herndon, F. C. Schmalstieg, D. L. Traber, and H. K. Hawkins, “Airway obstruction in sheep with burn and smoke inhalation injuries,” Am. J. Respir. Cell Mol. Biol. 29(3), 295–302 (2003).
[Crossref] [PubMed]

Seung, K. B.

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

Shepherd, K. L.

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

Shibuya, T. Y.

B. J. Wong, R. P. Jackson, S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, “In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients,” Laryngoscope 115(11), 1904–1911 (2005).
[Crossref] [PubMed]

Shishko, M.

B. J. Vakoc, M. Shishko, S. H. Yun, W. Y. Oh, M. J. Suter, A. E. Desjardins, J. A. Evans, N. S. Nishioka, G. J. Tearney, and B. E. Bouma, “Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video),” Gastrointest. Endosc. 65(6), 898–905 (2007).
[Crossref] [PubMed]

Shishkov, M.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

B. E. Bouma, G. J. Tearney, H. Yabushita, M. Shishkov, C. R. Kauffman, D. DeJoseph Gauthier, B. D. MacNeill, S. L. Houser, H. T. Aretz, E. F. Halpern, and I. K. Jang, “Evaluation of intracoronary stenting by intravascular optical coherence tomography,” Heart 89(3), 317–320 (2003).
[Crossref] [PubMed]

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

Shung, K. K.

J. Yin, H. C. Yang, X. Li, J. Zhang, Q. Zhou, C. Hu, K. K. Shung, and Z. Chen, “Integrated intravascular optical coherence tomography ultrasound imaging system,” J. Biomed. Opt. 15(1), 010512 (2010).
[Crossref] [PubMed]

Soejima, K.

R. A. Cox, A. S. Burke, K. Soejima, K. Murakami, J. Katahira, L. D. Traber, D. N. Herndon, F. C. Schmalstieg, D. L. Traber, and H. K. Hawkins, “Airway obstruction in sheep with burn and smoke inhalation injuries,” Am. J. Respir. Cell Mol. Biol. 29(3), 295–302 (2003).
[Crossref] [PubMed]

Song, Q.

Q. Song, J. Bai, M. K. Garvin, M. Sonka, J. M. Buatti, and X. Wu, “Optimal multiple surface segmentation with shape and context priors,” IEEE Trans. Med. Imaging 32(2), 376–386 (2013).
[Crossref] [PubMed]

Sonka, M.

Q. Song, J. Bai, M. K. Garvin, M. Sonka, J. M. Buatti, and X. Wu, “Optimal multiple surface segmentation with shape and context priors,” IEEE Trans. Med. Imaging 32(2), 376–386 (2013).
[Crossref] [PubMed]

M. K. Garvin, M. D. Abràmoff, X. Wu, S. R. Russell, T. L. Burns, and M. Sonka, “Automated 3-D intraretinal layer segmentation of macular spectral-domain optical coherence tomography images,” IEEE Trans. Med. Imaging 28(9), 1436–1447 (2009).
[Crossref] [PubMed]

M. K. Garvin, M. D. Abràmoff, R. Kardon, S. R. Russell, X. Wu, and M. Sonka, “Intraretinal layer segmentation of macular optical coherence tomography images using optimal 3-D graph search,” IEEE Trans. Med. Imaging 27(10), 1495–1505 (2008).
[Crossref] [PubMed]

K. Li, X. Wu, D. Z. Chen, and M. Sonka, “Optimal surface segmentation in volumetric images--a graph-theoretic approach,” IEEE Trans. Pattern Anal. Mach. Intell. 28(1), 119–134 (2006).
[Crossref] [PubMed]

Standish, B.

S. Lam, B. Standish, C. Baldwin, A. McWilliams, J. leRiche, A. Gazdar, A. I. Vitkin, V. Yang, N. Ikeda, and C. MacAulay, “In vivo optical coherence tomography imaging of preinvasive bronchial lesions,” Clin. Cancer Res. 14(7), 2006–2011 (2008).
[Crossref] [PubMed]

Su, E.

J. C. Jing, L. Chou, E. Su, B. J. Wong, and Z. Chen, “Anatomically correct visualization of the human upper airway using a high-speed long range optical coherence tomography system with an integrated positioning sensor,” Sci. Rep. 6(1), 39443 (2016).
[Crossref] [PubMed]

Su, J.

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

J. M. Ridgway, G. Ahuja, S. Guo, J. Su, U. Mahmood, Z. Chen, and B. Wong, “Imaging of the pediatric airway using optical coherence tomography,” Laryngoscope 117(12), 2206–2212 (2007).
[Crossref] [PubMed]

B. J. Wong, R. P. Jackson, S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, “In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients,” Laryngoscope 115(11), 1904–1911 (2005).
[Crossref] [PubMed]

Suter, M. J.

D. C. Adams, H. Pahlevaninezhad, M. V. Szabari, J. L. Cho, D. L. Hamilos, M. Kesimer, R. C. Boucher, A. D. Luster, B. D. Medoff, and M. J. Suter, “Automated segmentation and quantification of airway mucus with endobronchial optical coherence tomography,” Biomed. Opt. Express 8(10), 4729–4741 (2017).
[Crossref] [PubMed]

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

B. J. Vakoc, M. Shishko, S. H. Yun, W. Y. Oh, M. J. Suter, A. E. Desjardins, J. A. Evans, N. S. Nishioka, G. J. Tearney, and B. E. Bouma, “Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video),” Gastrointest. Endosc. 65(6), 898–905 (2007).
[Crossref] [PubMed]

Szabari, M. V.

Tao, Y. K.

Tearney, G. J.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

B. J. Vakoc, M. Shishko, S. H. Yun, W. Y. Oh, M. J. Suter, A. E. Desjardins, J. A. Evans, N. S. Nishioka, G. J. Tearney, and B. E. Bouma, “Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video),” Gastrointest. Endosc. 65(6), 898–905 (2007).
[Crossref] [PubMed]

B. E. Bouma, G. J. Tearney, H. Yabushita, M. Shishkov, C. R. Kauffman, D. DeJoseph Gauthier, B. D. MacNeill, S. L. Houser, H. T. Aretz, E. F. Halpern, and I. K. Jang, “Evaluation of intracoronary stenting by intravascular optical coherence tomography,” Heart 89(3), 317–320 (2003).
[Crossref] [PubMed]

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, and G. J. Tearney, “Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound,” J. Am. Coll. Cardiol. 39(4), 604–609 (2002).
[Crossref] [PubMed]

Traber, D. L.

R. A. Cox, A. S. Burke, K. Soejima, K. Murakami, J. Katahira, L. D. Traber, D. N. Herndon, F. C. Schmalstieg, D. L. Traber, and H. K. Hawkins, “Airway obstruction in sheep with burn and smoke inhalation injuries,” Am. J. Respir. Cell Mol. Biol. 29(3), 295–302 (2003).
[Crossref] [PubMed]

D. L. Traber, H. A. Linares, D. N. Herndon, and T. Prien, “The pathophysiology of inhalation injury--a review,” Burns 14(5), 357–364 (1988).
[Crossref] [PubMed]

Traber, L. D.

R. A. Cox, A. S. Burke, K. Soejima, K. Murakami, J. Katahira, L. D. Traber, D. N. Herndon, F. C. Schmalstieg, D. L. Traber, and H. K. Hawkins, “Airway obstruction in sheep with burn and smoke inhalation injuries,” Am. J. Respir. Cell Mol. Biol. 29(3), 295–302 (2003).
[Crossref] [PubMed]

Tran, A.

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

Tsai, T. H.

Tseng, L.

M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
[Crossref] [PubMed]

Vakoc, B. J.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

B. J. Vakoc, M. Shishko, S. H. Yun, W. Y. Oh, M. J. Suter, A. E. Desjardins, J. A. Evans, N. S. Nishioka, G. J. Tearney, and B. E. Bouma, “Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video),” Gastrointest. Endosc. 65(6), 898–905 (2007).
[Crossref] [PubMed]

Vitkin, A. I.

S. Lam, B. Standish, C. Baldwin, A. McWilliams, J. leRiche, A. Gazdar, A. I. Vitkin, V. Yang, N. Ikeda, and C. MacAulay, “In vivo optical coherence tomography imaging of preinvasive bronchial lesions,” Clin. Cancer Res. 14(7), 2006–2011 (2008).
[Crossref] [PubMed]

Wang, C.

Wang, L.

Wei, Y.

Wheatley, A.

M. Heydarian, S. Choy, A. Wheatley, D. McCormack, H. O. Coxson, S. Lam, and G. Parraga, “Automated segmentation of lung airway wall area measurements from bronchoscopic Optical Coherence Tomography imaging,” Proc. SPIE 7965(519), 79651M (2011).
[Crossref]

Wijesundara, K.

Williamson, J. P.

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

R. A. McLaughlin, J. P. Williamson, M. J. Phillips, J. J. Armstrong, S. Becker, D. R. Hillman, P. R. Eastwood, and D. D. Sampson, “Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway,” Opt. Express 16(22), 17521–17529 (2008).
[Crossref] [PubMed]

Wong, B.

J. M. Ridgway, G. Ahuja, S. Guo, J. Su, U. Mahmood, Z. Chen, and B. Wong, “Imaging of the pediatric airway using optical coherence tomography,” Laryngoscope 117(12), 2206–2212 (2007).
[Crossref] [PubMed]

Wong, B. J.

J. C. Jing, L. Chou, E. Su, B. J. Wong, and Z. Chen, “Anatomically correct visualization of the human upper airway using a high-speed long range optical coherence tomography system with an integrated positioning sensor,” Sci. Rep. 6(1), 39443 (2016).
[Crossref] [PubMed]

B. J. Wong, R. P. Jackson, S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, “In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients,” Laryngoscope 115(11), 1904–1911 (2005).
[Crossref] [PubMed]

Wong, B. J. F.

J. Jing, J. Zhang, A. C. Loy, B. J. F. Wong, and Z. Chen, “High-speed upper-airway imaging using full-range optical coherence tomography,” J. Biomed. Opt. 17(11), 110507 (2012).
[Crossref] [PubMed]

Wu, X.

Q. Song, J. Bai, M. K. Garvin, M. Sonka, J. M. Buatti, and X. Wu, “Optimal multiple surface segmentation with shape and context priors,” IEEE Trans. Med. Imaging 32(2), 376–386 (2013).
[Crossref] [PubMed]

M. K. Garvin, M. D. Abràmoff, X. Wu, S. R. Russell, T. L. Burns, and M. Sonka, “Automated 3-D intraretinal layer segmentation of macular spectral-domain optical coherence tomography images,” IEEE Trans. Med. Imaging 28(9), 1436–1447 (2009).
[Crossref] [PubMed]

M. K. Garvin, M. D. Abràmoff, R. Kardon, S. R. Russell, X. Wu, and M. Sonka, “Intraretinal layer segmentation of macular optical coherence tomography images using optimal 3-D graph search,” IEEE Trans. Med. Imaging 27(10), 1495–1505 (2008).
[Crossref] [PubMed]

K. Li, X. Wu, D. Z. Chen, and M. Sonka, “Optimal surface segmentation in volumetric images--a graph-theoretic approach,” IEEE Trans. Pattern Anal. Mach. Intell. 28(1), 119–134 (2006).
[Crossref] [PubMed]

Xu, Z.

Yabushita, H.

B. E. Bouma, G. J. Tearney, H. Yabushita, M. Shishkov, C. R. Kauffman, D. DeJoseph Gauthier, B. D. MacNeill, S. L. Houser, H. T. Aretz, E. F. Halpern, and I. K. Jang, “Evaluation of intracoronary stenting by intravascular optical coherence tomography,” Heart 89(3), 317–320 (2003).
[Crossref] [PubMed]

Yachimski, P. S.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

Yang, H. C.

J. Yin, H. C. Yang, X. Li, J. Zhang, Q. Zhou, C. Hu, K. K. Shung, and Z. Chen, “Integrated intravascular optical coherence tomography ultrasound imaging system,” J. Biomed. Opt. 15(1), 010512 (2010).
[Crossref] [PubMed]

Yang, N.

Yang, Q.

Yang, T.

Yang, V.

S. Lam, B. Standish, C. Baldwin, A. McWilliams, J. leRiche, A. Gazdar, A. I. Vitkin, V. Yang, N. Ikeda, and C. MacAulay, “In vivo optical coherence tomography imaging of preinvasive bronchial lesions,” Clin. Cancer Res. 14(7), 2006–2011 (2008).
[Crossref] [PubMed]

Yin, J.

S.-W. Lee, A. E. Heidary, D. Yoon, D. Mukai, T. Ramalingam, S. Mahon, J. Yin, J. Jing, G. Liu, Z. Chen, and M. Brenner, “Quantification of airway thickness changes in smoke-inhalation injury using in-vivo 3-D endoscopic frequency-domain optical coherence tomography,” Biomed. Opt. Express 2(2), 243–254 (2011).
[Crossref] [PubMed]

J. Yin, H. C. Yang, X. Li, J. Zhang, Q. Zhou, C. Hu, K. K. Shung, and Z. Chen, “Integrated intravascular optical coherence tomography ultrasound imaging system,” J. Biomed. Opt. 15(1), 010512 (2010).
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J. Yin, G. Liu, J. Zhang, L. Yu, S. Mahon, D. Mukai, M. Brenner, and Z. Chen, “In vivo early detection of smoke-induced airway injury using three-dimensional swept-source optical coherence tomography,” J. Biomed. Opt. 14(6), 060503 (2009).
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Yoon, D.

Yu, J.

Yu, L.

J. Yin, G. Liu, J. Zhang, L. Yu, S. Mahon, D. Mukai, M. Brenner, and Z. Chen, “In vivo early detection of smoke-induced airway injury using three-dimensional swept-source optical coherence tomography,” J. Biomed. Opt. 14(6), 060503 (2009).
[Crossref] [PubMed]

Yu, S.

Yuan, W.

Yun, S. H.

B. J. Vakoc, M. Shishko, S. H. Yun, W. Y. Oh, M. J. Suter, A. E. Desjardins, J. A. Evans, N. S. Nishioka, G. J. Tearney, and B. E. Bouma, “Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video),” Gastrointest. Endosc. 65(6), 898–905 (2007).
[Crossref] [PubMed]

Zdanski, C.

Zhang, B.

Zhang, J.

J. Zhang, W. Yuan, W. Liang, S. Yu, Y. Liang, Z. Xu, Y. Wei, and X. Li, “Automatic and robust segmentation of endoscopic OCT images and optical staining,” Biomed. Opt. Express 8(5), 2697–2708 (2017).
[Crossref] [PubMed]

J. Jing, J. Zhang, A. C. Loy, B. J. F. Wong, and Z. Chen, “High-speed upper-airway imaging using full-range optical coherence tomography,” J. Biomed. Opt. 17(11), 110507 (2012).
[Crossref] [PubMed]

J. Yin, H. C. Yang, X. Li, J. Zhang, Q. Zhou, C. Hu, K. K. Shung, and Z. Chen, “Integrated intravascular optical coherence tomography ultrasound imaging system,” J. Biomed. Opt. 15(1), 010512 (2010).
[Crossref] [PubMed]

J. Yin, G. Liu, J. Zhang, L. Yu, S. Mahon, D. Mukai, M. Brenner, and Z. Chen, “In vivo early detection of smoke-induced airway injury using three-dimensional swept-source optical coherence tomography,” J. Biomed. Opt. 14(6), 060503 (2009).
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J. Zhang, J. S. Nelson, and Z. Chen, “Removal of a mirror image and enhancement of the signal-to-noise ratio in Fourier-domain optical coherence tomography using an electro-optic phase modulator,” Opt. Lett. 30(2), 147–149 (2005).
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Zhang, M.

Zhang, X.

Zhou, C.

Zhou, Q.

J. Yin, H. C. Yang, X. Li, J. Zhang, Q. Zhou, C. Hu, K. K. Shung, and Z. Chen, “Integrated intravascular optical coherence tomography ultrasound imaging system,” J. Biomed. Opt. 15(1), 010512 (2010).
[Crossref] [PubMed]

Zhu, J.

Y. Li, J. Jing, E. Heidari, J. Zhu, Y. Qu, and Z. Chen, “Intravascular optical coherence tomography for characterization of atherosclerosis with a 1.7 micron swept-source laser,” Sci. Rep. 7(1), 14525 (2017).
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S. Huang, Z. Piao, J. Zhu, F. Lu, and Z. Chen, “In vivo microvascular network imaging of the human retina combined with an automatic three-dimensional segmentation method,” J. Biomed. Opt. 20(7), 076003 (2015).
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L. Qi, S. Huang, A. E. Heidari, C. Dai, J. Zhu, X. Zhang, and Z. Chen, “Automatic airway wall segmentation and thickness measurement for long-range optical coherence tomography images,” Opt. Express 23(26), 33992–34006 (2015).
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Am. J. Respir. Cell Mol. Biol. (1)

R. A. Cox, A. S. Burke, K. Soejima, K. Murakami, J. Katahira, L. D. Traber, D. N. Herndon, F. C. Schmalstieg, D. L. Traber, and H. K. Hawkins, “Airway obstruction in sheep with burn and smoke inhalation injuries,” Am. J. Respir. Cell Mol. Biol. 29(3), 295–302 (2003).
[Crossref] [PubMed]

Am. J. Respir. Crit. Care Med. (1)

J. P. Williamson, R. A. McLaughlin, W. J. Noffsinger, A. L. James, V. A. Baker, A. Curatolo, J. J. Armstrong, A. Regli, K. L. Shepherd, G. B. Marks, D. D. Sampson, D. R. Hillman, and P. R. Eastwood, “Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography,” Am. J. Respir. Crit. Care Med. 183(5), 612–619 (2011).
[Crossref] [PubMed]

Biomed. Opt. Express (7)

T. H. Tsai, B. Potsaid, Y. K. Tao, V. Jayaraman, J. Jiang, P. J. Heim, M. F. Kraus, C. Zhou, J. Hornegger, H. Mashimo, A. E. Cable, and J. G. Fujimoto, “Ultrahigh speed endoscopic optical coherence tomography using micromotor imaging catheter and VCSEL technology,” Biomed. Opt. Express 4(7), 1119–1132 (2013).
[Crossref] [PubMed]

K. Wijesundara, C. Zdanski, J. Kimbell, H. Price, N. Iftimia, and A. L. Oldenburg, “Quantitative upper airway endoscopy with swept-source anatomical optical coherence tomography,” Biomed. Opt. Express 5(3), 788–799 (2014).
[Crossref] [PubMed]

S.-W. Lee, A. E. Heidary, D. Yoon, D. Mukai, T. Ramalingam, S. Mahon, J. Yin, J. Jing, G. Liu, Z. Chen, and M. Brenner, “Quantification of airway thickness changes in smoke-inhalation injury using in-vivo 3-D endoscopic frequency-domain optical coherence tomography,” Biomed. Opt. Express 2(2), 243–254 (2011).
[Crossref] [PubMed]

D. C. Adams, H. Pahlevaninezhad, M. V. Szabari, J. L. Cho, D. L. Hamilos, M. Kesimer, R. C. Boucher, A. D. Luster, B. D. Medoff, and M. J. Suter, “Automated segmentation and quantification of airway mucus with endobronchial optical coherence tomography,” Biomed. Opt. Express 8(10), 4729–4741 (2017).
[Crossref] [PubMed]

J. Zhang, W. Yuan, W. Liang, S. Yu, Y. Liang, Z. Xu, Y. Wei, and X. Li, “Automatic and robust segmentation of endoscopic OCT images and optical staining,” Biomed. Opt. Express 8(5), 2697–2708 (2017).
[Crossref] [PubMed]

M. Gan, C. Wang, T. Yang, N. Yang, M. Zhang, W. Yuan, X. Li, and L. Wang, “Robust layer segmentation of esophageal OCT images based on graph search using edge-enhanced weights,” Biomed. Opt. Express 9(9), 4481–4495 (2018).
[Crossref]

M. Gan, C. Wang, T. Yang, N. Yang, M. Zhang, W. Yuan, X. Li, and L. Wang, “Robust layer segmentation of esophageal OCT images based on graph search using edge-enhanced weights,” Biomed. Opt. Express 9(9), 4481–4495 (2018).
[Crossref]

Burns (1)

D. L. Traber, H. A. Linares, D. N. Herndon, and T. Prien, “The pathophysiology of inhalation injury--a review,” Burns 14(5), 357–364 (1988).
[Crossref] [PubMed]

Clin. Cancer Res. (1)

S. Lam, B. Standish, C. Baldwin, A. McWilliams, J. leRiche, A. Gazdar, A. I. Vitkin, V. Yang, N. Ikeda, and C. MacAulay, “In vivo optical coherence tomography imaging of preinvasive bronchial lesions,” Clin. Cancer Res. 14(7), 2006–2011 (2008).
[Crossref] [PubMed]

Gastrointest. Endosc. (2)

B. J. Vakoc, M. Shishko, S. H. Yun, W. Y. Oh, M. J. Suter, A. E. Desjardins, J. A. Evans, N. S. Nishioka, G. J. Tearney, and B. E. Bouma, “Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video),” Gastrointest. Endosc. 65(6), 898–905 (2007).
[Crossref] [PubMed]

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
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Heart (1)

B. E. Bouma, G. J. Tearney, H. Yabushita, M. Shishkov, C. R. Kauffman, D. DeJoseph Gauthier, B. D. MacNeill, S. L. Houser, H. T. Aretz, E. F. Halpern, and I. K. Jang, “Evaluation of intracoronary stenting by intravascular optical coherence tomography,” Heart 89(3), 317–320 (2003).
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IEEE Trans. Med. Imaging (4)

T. B. Dubose, D. Cunefare, E. Cole, P. Milanfar, J. A. Izatt, and S. Farsiu, “Statistical models of signal and noise and fundamental limits of segmentation accuracy in retinal optical coherence tomography,” IEEE Trans. Med. Imaging 37(9), 1978–1988 (2018).
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M. K. Garvin, M. D. Abràmoff, X. Wu, S. R. Russell, T. L. Burns, and M. Sonka, “Automated 3-D intraretinal layer segmentation of macular spectral-domain optical coherence tomography images,” IEEE Trans. Med. Imaging 28(9), 1436–1447 (2009).
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M. K. Garvin, M. D. Abràmoff, R. Kardon, S. R. Russell, X. Wu, and M. Sonka, “Intraretinal layer segmentation of macular optical coherence tomography images using optimal 3-D graph search,” IEEE Trans. Med. Imaging 27(10), 1495–1505 (2008).
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IEEE Trans. Pattern Anal. Mach. Intell. (2)

K. Li, X. Wu, D. Z. Chen, and M. Sonka, “Optimal surface segmentation in volumetric images--a graph-theoretic approach,” IEEE Trans. Pattern Anal. Mach. Intell. 28(1), 119–134 (2006).
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J. Am. Coll. Cardiol. (1)

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J. Biomed. Opt. (6)

J. Yin, H. C. Yang, X. Li, J. Zhang, Q. Zhou, C. Hu, K. K. Shung, and Z. Chen, “Integrated intravascular optical coherence tomography ultrasound imaging system,” J. Biomed. Opt. 15(1), 010512 (2010).
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M. Brenner, K. Kreuter, J. Ju, S. Mahon, L. Tseng, D. Mukai, T. Burney, S. Guo, J. Su, A. Tran, A. Batchinsky, L. C. Cancio, N. Narula, and Z. Chen, “In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model,” J. Biomed. Opt. 13(3), 034001 (2008).
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J. Yin, G. Liu, J. Zhang, L. Yu, S. Mahon, D. Mukai, M. Brenner, and Z. Chen, “In vivo early detection of smoke-induced airway injury using three-dimensional swept-source optical coherence tomography,” J. Biomed. Opt. 14(6), 060503 (2009).
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Laryngoscope (2)

J. M. Ridgway, G. Ahuja, S. Guo, J. Su, U. Mahmood, Z. Chen, and B. Wong, “Imaging of the pediatric airway using optical coherence tomography,” Laryngoscope 117(12), 2206–2212 (2007).
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Opt. Express (2)

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Proc. SPIE (2)

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Sci. Rep. (2)

Y. Li, J. Jing, E. Heidari, J. Zhu, Y. Qu, and Z. Chen, “Intravascular optical coherence tomography for characterization of atherosclerosis with a 1.7 micron swept-source laser,” Sci. Rep. 7(1), 14525 (2017).
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Figures (11)

Fig. 1
Fig. 1 Typical endoscopic airway OCT images. Various artifacts were presented: (a) normal case with flat tissue surface (the imaging probe is in the center of the airway), noise and saturated A-lines are presented; (b) curvature of the airway wall changes dramatically when the probe is not in the center of the airway; (c) edge blurring is induced when the probe sheath is in touch of the airway tissue (inset shows the anatomy of the airway wall).
Fig. 2
Fig. 2 Flowchart of the proposed 3D segmentation method
Fig. 3
Fig. 3 The pre-processing pipeline to suppress artifacts and obtain the surface slope: the final results of this step are the slope values (both the x and y directions) at each A-line position along the airway lumen surface and the sheath-removed images. For illustration, the slope values along the x-direction are color-coded in the last figure.
Fig. 4
Fig. 4 (a) and (b) shows the graph construction in the optimal 3D GS algorithm, illustrating the three different types of arcs connecting the vertices; (c) the principle of the proposed slope-constrained graph construction: the inter-column arcs varies with the slope of the tissue surface; (d) and (e): the original 3D GS algorithm failed to detect edges with large slope variation; (f) the edge is detected accurately with the adaptive slope constraint.
Fig. 5
Fig. 5 Multi-surface segmentation in our method: (a) and (c) are the flattened regions for detecting the mucosa/submucosa and the submucosa/cartilage boundaries, (b) and (d) are the detection results. (e) is the final segmentation result.
Fig. 6
Fig. 6 The two different platforms for image acquisition: OCT systems with phase modulation for extended imaging range [15] (a) and with a VESEL light source [17] (b). MZI: Mach-Zehnder interferometer.
Fig. 7
Fig. 7 The segmentation of the airway wall: (a) and (b) are representative results of the human airway data set. (c) and (d) are representative results of the sheep airway data set.
Fig. 8
Fig. 8 Single surface 3D reconstruction: (a) the original image stack from the sheep data set, (b) 3D reconstruction of the airway lumen detected by the proposed segmentation method, (c) 3D reconstruction of the airway lumen detected by the dynamic programming method.
Fig. 9
Fig. 9 The segmentation of the airway structure: (a) are two consecutive test images in the pig airway data set, (b) are the segmentation results for one layer (the airway structure) by using different methods.
Fig. 10
Fig. 10 The segmentation of the mucosa and submucosa layers: (a) are two test images in the pig and sheep airway data set, (b) are the segmentation results for the mucosa and submucosa layers by using different methods.
Fig. 11
Fig. 11 Multiple surface 3D reconstruction: (a) the original image from the pig data set; (b) and (c) are the 3D reconstruction of the entire airway segmented by the proposed method and the DP method, respectively; (d) to (f) are the 3D visualization of the airway lumen surface, the mucosa/submucosa boundary, and the submucosa/cartilage boundary detected by the proposed method, respectively; (g) to (i) are the corresponding surfaces detected by the DP method.

Tables (3)

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Table 1 Data sets used in the experiments

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Table 2 RMSE and MAD values of three comparing methods

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Table 3 Dice’s coefficients of three comparing methods

Equations (8)

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P ij =| z ij+1 z ij x ij+1 x ij |,i{1,2,..X},j{1,2,..Y},
S i =[ m i +2.6 v i +c],i{1,2,..X},
m i = 1 Y j=1 Y P ij
v i = 1 Y j=1 Y ( P ij m i ) 2 ,
W(x,y,z)={ c(x,y,z) z=0 c(x,y,z)c(x,y,z1) otherwise
RMSE= 1 n i=1 n ( G i M i ) 2
MAD= 1 n i=1 n | G i M i |
DSC= 2| S a S m | | S a |+| S m |

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