The approach uncovered by Mohler et al. to develop CARS is original and probably the most promising for future applications. Using two frequency combs from two different lasers with around 1 GHz repetition rate, the speed of acquisition of single spectra can be boosted to the kHz range. The signal-to-noise ratio, the broadband coverage and the resolution achieved are very promising for detecting and distinguishing a large range of biological and chemical species. Developing the technique even further with higher repetition rates and stronger pulses demands some technological development, but the perspective of video-rate hyper-spectral imaging of living cells with dual-comb CARS is now at reach.
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